منابع مشابه
Adaptive algorithm of automated annotation
MOTIVATION It is common knowledge that the avalanche of data arriving from the sequencing projects cannot be annotated either experimentally or manually by experts. The need for a reliable and convenient tool for automated sequence annotation is broadly recognized. RESULTS Here, we describe the Adaptive Algorithm of Automated Annotation (A(4)) based on a statistical approach to this problem. ...
متن کاملSliceMap: an algorithm for automated brain region annotation
Summary Many neurodegenerative disorders, such as Alzheimer's Disease, pertain to or spread from specific sites of the brain. Hence, accurate disease staging or therapy assessment in transgenic model mice demands automated analysis of selected brain regions. To address this need, we have developed an algorithm, termed SliceMap, that enables contextual quantification by mapping anatomical inform...
متن کاملKnowledge-based voting algorithm for automated protein functional annotation.
Automated annotation of high-throughput genome sequences is one of the earliest steps toward a comprehensive understanding of the dynamic behavior of living organisms. However, the step is often error-prone because of its underlying algorithms, which rely mainly on a simple similarity analysis, and lack of guidance from biological rules. We present herein a knowledge-based protein annotation al...
متن کاملValidation of Automated Protein Annotation
Given the large amount of data stored in biological databases, the management of uncertainty and incompleteness in them is a non-trivial problem. To cope with the large amount of sequences being produced, a significant number of genes and proteins have been functionally characterized by automated tools. However, these tools have also produced a significant number of misannotations that are now ...
متن کاملAutomated annotation of natural images using an extended annotation model
Automated annotation of digital images remains a highly challenging task being used for indexing, retrieving, and understanding of large collections of image data. This paper presents an original extension of an image annotation model using an object oriented approach. The proposed model is an extension of an efficient annotation model called Cross Media Relevance Model. Image’s regions are des...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2002
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/18.6.838